Prayogic Rasayan 2021, 5, 43-48
DOI: https://www.doi.org/10.53023/p.rasayan-20210930
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Abstract
Prayogic Rasayan 2021, 5, 49-56
DOI: https://www.doi.org/10.53023/p.rasayan-20210715
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Abstract
Prayogic Rasayan 2021, 5, 57-59
DOI: https://www.doi.org/10.53023/p.rasayan-20210917
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Abstract
Prayogic Rasayan 2021, 5, 60-69
DOI: https://www.doi.org/10.53023/p.rasayan-20211115
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Abstract
FeCl3-catalyzed cyclization of arylvinylcarbinols for the synthesis of [6,5,6]-carbotricyclic core sharing an all-carbon quaternary center has been described in this full article. A careful mechanistic details suggest that the reaction follows a stepwise mechanism via the intermediacy of arylallyl carbocationic species. The carbocation subsequently reacts with an adjacent aromatic ring to form [6,5,6]-carbotricyclic scaffold of abeo-abietane diterpenoids. The methodology works under mild conditions to afford a variety of carbotricyclic core ingood to excellent yields (up to 99% yield). Our strategy has been applied to a concise synthesis of a number of structurally intriguing naturally occurring taiwaniaquinoids, ±-taiwaniaquinol F (1a), ±-taiwaniaquinol B (1b), ±-dichronanone(1c), ±-taiwaniaquinone H (1d) and unnatural ±-5-epi-taiwaniaquinoneG (epi-1e).
Prayogic Rasayan 2021, 5, 70-75
DOI: https://www.doi.org/10.53023/p.rasayan-20211102
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Abstract
TThis study was conducted to evaluate the in vitro Ultra-Violet(UV) filtering and anti-tyrosinase potential in several medicinal plants. The methanolic extract of Tagetes erecta has displayed a sun protection factor (SPF) of 40 and was found to be photostable. Furthermore, an extreamly potent tyrosinase inhibition (IC50 = 48.27 µg/mL) as well as antioxidant activity (EC50 = 14.82 µg/mL) were observed for the same extract revealing the high potential for the development of herbal cosmetics.