VOL-5 ISSUE-1, January 2021

Serial NoTitle & Author NameViewsDownloads
1.Palladium Catalyzed Intramolecular Cyclization and C-H Activation Reaction Interesting Tool for the Synthesis of Some Exquisite Molecules

By Jayanta Kumar Ray

Pages : 1-6

We have successfully investigated the palladium catalyzed cyclization in diene system to the formation of three unusual products. By varying the reaction conditions, we observed the formation of fused cyclopentane-cyclopropane rings, fused cyclopentane-cyclopentane rings or benzene ring formation from similar types of diene substrates. The most unexpected and unusual step, the formation of cyclopropane, was studied using density functional theory based calculations.

2.Lycopodium Alkaloids from Thai Club Mosses

By Chuleeporn Ngernnak, Wachirasak Thaisaeng, Wanlaya Thamnarak, Somsak Ruchirawat, Nopporn Thasana

Pages : 7-15

This review focuses on the structural classification of t he Lycopodium alkaloids (LAs) isolated from seven species of Thai club mosses and their biological activities, especially acetylcholinesterase inhibitory activity.The structures of 38 LAs are presented and some isolated LAs were potent acetylcholinesterase (AChE) inhibitors. The content of huperzine A in the club moss species was evaluated for biological activities.

3.Green synthesis of zinc oxide nanoparticles, their characterization and utilization for photocatalytic removal of methylene blue

By Rahul Patwa, Nabanita Saha, Petr Sáha

Pages : 23-26

We report a facile synthesis of zinc oxide nanoparticles by green chemistry utilizing fresh lemon juice, zinc acetate and ethylene glycol. The prepared ZnO NPs were characterized using FTIR spectroscopy, X-ray diffraction analysis, DLS, FESEM and EDAX. The particles were found to be hexagonal wurtzite form having average particle size ~250 nm. The developed ZnO-NPs showed photocatalytic degradation of the artificial dye Methylene Blue under UV light irradiation at 365 nm.

4.Liquid Crystals: A Fascinating Fourth State of Matter

By Sachin A. Bhat, Madhu Babu Kanakala, Channabasaveshwar V.Yelamaggad

Pages : 27-36

Liquid crystals (LCs) are a distinct phase of matter whose structural order is intermediate between conventional liquids and solids. They have attracted considerable attention not only because they form the basis of every living being but also due to their ability to show a range of unique properties that are promising from the viewpoints of both fundamental research and applied science.

5.Total Synthesis of Hapalindole Alkaloids via Cascade Prins-type Cyclization

By Samrat Sahu and Modhu Sudan Maji

Pages : 37-42

This highlight describes our recently reported method of cascade Prins-type cyclization method. Structural complexity and interesting biological activity made hapalindole alkaloid an attractive choice to synthetic chemists. We recently disclosed a redox-neutral, biomimetic Prins-type cyclization between indole and an aldehyde bearing a terminal ene-promoter. Total synthesis of seven hapalindole alkaloids and formal synthesis of two alkaloids were accomplished in a stereodivergent manner.