VOL-1 ISSUE-2, July 2017

Serial NoTitle & Author NameViewsDownloads
1.Self-assembly study of ammonium oleanolate and generation of gel–gold nanoparticle hybrid material

By Braja Gopal Bag and Subhajit Das

Pages : 43-47

A solution of oleanolic acid, a renewable nano-sized monohydroxy triterpenic acid in tetrahydrofuran, transformed into a gel instantly at room temperature on treatment with aqueous ammonia. Study of the self-assembly properties of ammonium oleanolate in water and aqueous solvent mixtures indicated that it self-assembles in the aqueous solvent mixtures forming gels in DMSO-water and DMF-water. Fibrillar networks with optical birefringence properties were observed by polarized optical microscop

2.Nanotechnology in psoriasis

By Voshavar Chandrashekhar and Srujan Marepally

Pages : 48-53

Psoriasis is a chronic autoimmune skin disease with a substantial negative impact on the patient’s quality of life. To date, a wide range of treatment options such as topical delivery of corticosteroids, vitamin D derivatives, phototherapy, and administration of immuno-modulators are available. However, these approaches have major limitations such as a plethora of side effects and skin develops resistance to treatments over time. In addition, therapeutic outcome of psoriasis treatments also ca

3.A bioactive diterpene; Nasimalun A from Croton oblongifolius Roxb.

By Kanchana Wijesekera

Pages : 54-57

A clerodane type diterpene, nasimalun A was isolated from a dichloromethane extract of the leaves of Croton oblongifolius Roxb. Nasimalun A showed moderate cytotoxicity toward MOLT- 3 cell line with IC50 value of 26.44 µg/mL. Furthermore, nasimalun A showed minimum inhibitory concentration (MIC) of 50, 12.5, and100 μg/mL for Bacillus cereus and both Staphylococcus aureus, and Staphylococcus epidermidis respectively.

4.Glucocorticoid receptor: A potent cellular & gene therapy target for cancer and cancer stem cells

By Rajkumar Banerjee

Pages : 58-60

Glucocorticoid receptor (GR) is expressed in the cytoplasm of almost all cells, if not all of cancer and non-cancer cells. Moreover, unlike many other factors implicated with cancer, it is neither over-expressed nor is it expressed on cell-membrane surface to qualify logically as a viable target for treating cancer. GR is importantly linked with alternate pathway of energy metabolism in cancer cells and our research indicated that cancer cells possibly tend to avoid activation of GR which would

5.Study of Antioxidant Property of the Endosperm Extract of Borassus flabellifer (Taal) and its use in the green synthesis of Gold nanoparticles

By Sk Nurul Hasan and Braja Gopal Bag

Pages : 61-65

The antioxidant activity of the endosperm extract of Borassus flabellifer (commonly known as Taal) has been studied against a long lived 2,2-diphenylpicrylhydrazyl (DPPH) radical at room temperature. The phytochemicals present in the endosperm extract have been utilized for the synthesis of stable gold nanoparticles at room temperature under very mild conditions. The synthesized gold nanoparticles were characterized by Surface Plasmon Resonance spectroscopy, High resolution transmission electro